Temazepam Options

Temazepam Options

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Use Caution/Keep track of. Ethinyl estradiol may possibly inhibit the clearance of benzodiazepines that undertake oxidation, thus raising serum concentrations of concomitantly administered benzodiazepines.

atazanavir will increase the stage or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

Check Carefully (1)mitotane decreases levels of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mitotane is a strong inducer of cytochrome P-4503A4; keep an eye on when coadministered with CYP3A4 substrates for probable dosage changes.

Observe Closely (1)glycerol phenylbutyrate will lessen the extent or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

griseofulvin will decrease the level or outcome of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

Observe Carefully (1)berotralstat will improve the level or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Check or titrate substrate dose when berotralstat is coadministered with slender therapeutic index medication which have been CYP3A substrates.

eluxadoline improves amounts of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Warning when CYP3A substrates that have a narrow therapeutic index are coadministered with eluxadoline.

hydrocortisone will lessen the extent or impact of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

Worsening of sleeplessness or perhaps the emergence of latest imagining or actions abnormalities often is the consequence of the unrecognized psychiatric or Actual physical problem. These kinds of results have emerged in the course of the study course of cure with sedative-hypnotic medicine. For the reason that a lot of the vital adverse outcomes of sedative-hypnotics seem like dose-associated (see PRECAUTIONS and DOSAGE AND ADMINISTRATION), it is important to utilize the smallest doable productive dose, particularly in the elderly.

ritonavir will improve the level or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

itraconazole will enhance the degree or influence of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Both equally medication will raise QT interval

Benzodiazepines interact at GABAA sites and opioids interact mainly at mu receptors. When benzodiazepines and opioids are put together, the prospective for benzodiazepines to appreciably worsen opioid-related respiratory depression exists.

Observe neonates subjected to estazolam all through pregnancy or labor for indications of sedation and Suvorexant observe neonates subjected to estazolam through pregnancy for indications of withdrawal; deal with these neonates accordingly.

chloramphenicol will enhance the degree or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.